Education
- Post-doctorate, Mayo Clinic, Rochester, Minnesota, 1984
- Post-doctorate, University of Utah Medical School, 1977
- Ph.D., University of California, 1976
Research Interests
Immortalization of avian cells for vaccine substrates, reverse genetic engineering of biomarker-tagged avian metapneumovirus, molecular mechanisms
of cellular senescence and immortalization, regulation of cell cycle
events, cloning of growth specific sequences, avian endocrinology,
recombinant protein production.
Graduate Students
- Daniela Blini, M.S, Animal Sciences
- Lance Hellstrom, M.S, Animal Sciences
- Hurley Huang, M.S., Animal Sciences
- Robyn Gangl, M.S., CMB
Teaching
- CFANS 1501: Biotechnology, People & Environment (Animal Biotechnology Section)
- CFANS 4009W: Senior Thesis ScAg (course coordinator)
- ANSC 4096: Internship (internship coordinator)
- ANSC 8131/CMB 8335: Molecular Biology Techniques (course coordinator)
- ANSC/CMB 8340: Mechanisms of Hormone Action (co-instructor)
- ANSC 8510: Graduate Seminar (course coordinator)
- BIOC 4185: Laboratory in Molecular Biology and Biotechnology (co-instructor)
Outreach
- Faculty for summer LSSURP, Lake Itasca, MN
- Minnesota Representative - 1170 Annual Meeting
Patents
- Immortalized cell lines protein production. Patent # 6,207,415 Issued 3/27/01.
- Immortalized cell lines for virus growth. Patent # 5,985,642 Issued
11/16/99.
- Immortalized cell lines for virus growth. Patent # 5,879,924 Issued
3/9/99.
- Method for immortalizing cells. Patent # 5,830,723 Issued 11/03/98.
- Immortalized cell lines for virus growth. Patent # 5,672,485 Issued
9/30/97.
Awards
- University of Minnesota Graduate-Professional Teaching Award, Academy of Distinguished Teachers - 2008
- Outstanding Graduate Faculty Award, Department of Animal Science - 2000, 2005-06
Affiliations
- Comparative Molecular Bioscience Graduate Program, University of Minnesota
- Veterinary Medicine Graduate Program, University of Minnesota
Publications (2004-2008)
- Refereed Articles -
Kong B.-W., D.F. Carlson, S.C. Fahrenkrug, and D.N. Foster. 2008. Application of the Sleeping Beauty transposon system to avian cells. Animal Genet. 39:180-186.
Kong B.-W., L.K. Foster, and D.N. Foster. 2008. A method for the rapid isolation of virus from cultured cells. BioTech. 44:97-99.
Kong B.-W., L.K. Foster, and D.N. Foster. 2008. Species-specific deletion of the viral attachment glycoprotein of avian metapneumovirus. Virus Res. 132:114-121.
Paulin-Curlee, G.G., S. Sreevatsan, R.S. Singer, R. Isaacson, J. Reneau, R. Bey, and D. Foster. 2008. Molecular subtyping of mastitis associated Klebsiella pneumonia isolates show high levels of diversity within and between dairy herds. J. Dairy Sci. 91:554-563.
Tirumurugaan, K.G., B.N. Kang, R.A. Panettieri, D.N. Foster, T.F. Walseth, and M.S. Kannan. 2008. Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-alpha and dexamethasone. Respiratory Res. 9:26.
Vadnais, M.L., D.N. Foster, and K.P. Roberts. 2008. Molecular cloning and expression of the Crisp family of proteins in the boar. Biol. Reprod. 79:1129-1134.
Clark, K.J., D.F. Carlson, L. Foster, B-W. Kong, D.N. Foster, and S.C. Fahrenkrug. 2007. Enzymatic engineering of the porcine genome with transposons and recombinases. BMC Biotech. 7:42.
Kong B.-W., L.K. Foster, and D.N. Foster. 2007. Establishment of an immortal turkey turbinate cell line suitable for avian metapneumovirus propagation. Virus Res. 127:106-115.
Paulin-Curlee, G.G., R.S. Singer, S. Sreevatsan, R. Isaacson, J. Reneau, D. Foster, and R. Bey. 2007. Genetic diversity of mastitis-associated Klebsiella pneumoniae in dairy cows. J. Dairy Sci. 90:3681-3689.
Christman, S.A., B.-W. Kong, M.M. Landry, H. Kim, and D.N. Foster. 2006. Contributions of differential p53 expression in the spontaneous immortalization of a chicken embryo fibroblast cell line. BMC Cell Biol. 7:27.
Hunt, H.D., R.M. Goto, D.N. Foster, L.D. Bacon, and M.M. Miller. 2006. At least one YMHCI molecule in the chicken is alloimmunogenic and dynamically expressed on spleen cells during development. Immunogenetics 58:297-307.
Kim, S-H., J. Rowe, H. Fujii. R. Jones, B. Schmierer, B-W Kong, K. Kuchler, D. Foster, D. Ish-Horowicz, and G. Peters. 2006. Upregulation of chicken p15INK4b at senescence and in the developing brain. J. Cell Sci. 119:2435-2443.
Kong B.-W., L.K. Foster, and D.N. Foster. 2006. Comparison of avian cell substrates for propagating subtype C avian metapneumovirus. Virus Res. 116:58-68.
Alghamdi, A.S. and D.N. Foster. 2005. Seminal DNase frees spermatozoa
entangled in neutrophil extracellular traps. Biol. Reprod. 73:1174-1181.
Alghamdi, A.S., D.N. Foster, C.S. Carlson, and M.H.T. Troedsson. 2005.
Nitric oxide levels and nitric oxide synthase expression in uterine
samples from mares susceptible and resistant to persistent breeding
induced endometritis. J. Reprod. Immunol. 53:230-237.
Alghamdi, A.S., S. Madill, and D.N. Foster. 2005. Seminal plasma improves fertility of frozen equine semen. Animal Reprod. Sci. 89:242-245.
Christman, S.A., B.-W. Kong, M.M. Landry, and D.N. Foster. 2005.
Chicken embryo extract mitigates growth and morphological changes in a
spontaneously immortalized chicken embryo fibroblast cell line. Poultry Sci.
84:1423-1431.
Christman, S.A., B.-W. Kong, M.M. Landry, H. Kim, and D.N. Foster.
2005. Modulations of p53 expression and its role in the converion to a fully immortalized chicken embryo fibroblast line. FEBS Letters 579:6705-6715.
Alghamdi, A.S.,
D.N. Foster, and M.H.T. Troedsson. 2004. Equine seminal plasma reduces
sperm binding to polymorphonuclear neutrophils (PMNs) and improves
the fertility of fresh semen inseminated into inflamed uteri. Reproduction
127:593-600.
You S., H. Kim, B.-W. Kong, H. Kim, and D.N. Foster. 2004. The role of MnSOD and catalase in response to antimycin A induced oxidative stress in immortal DF-1 cells. Molec. Cells. 18:220-229.
- Presentations at Professional Meetings -
Foster, D. 2004. Mechanisms of cellular immortalization. Biology Dept., Mankato State University, Mankato, MN. Feb. 2004.
- Abstracts-
Kong, B-W., L.K. Foster, and D.N. Foster. 2006. Species specific deletion of the viral glycoprotein of avian metapneumovirus. American Virology Assoc., July 16, 2006, Madison, WI.
Kong, B-W. and D. N. Foster. 2005. Establishment of an Immortal Turkey Turbinate Cell Line as a Homologous Cellular Substrate for the Propagation of Avian Metapneumovirus American Society for Microbiology, Atlanta GA
Paulin-Curlee, G., R. Bey, R. Singer, D. Foster, R. Isaacson, and J. Reneau. 2005. Molecular epidemiology of Klebsiella pneumoniae in dairy herds. 48th AAVLD Meeting.
Paulin-Curlee, G., R. Singer, R. Bey, R. Isaacson, D. Foster, and J. Reneau. 2005 Genomic diversity in Klebsiella pneumoniae strains isolated from dairy herds. CRWAD Meeting, Chicago, IL.
Carlson, D., B.-W. Kong, A. Geurts, D. Shiroma, C. Steer, S.M. O’Grady, B. Herring, D.N. Foster, and S.C. Fahrenkrug. 2004. Transgenic and chromosome engineering in pigs. 2nd Annual International Conference on Transposition and Animal Biotechnology, Minneapolis, MN. June 1-2.
Kong, B.-W., A. Geurts, P.D. Lobitz, D.N. Foster, and S.C. Fahrenkrug. 2004. Application of the Sleeping Beauty transposon system to livestock transgenesis. Poster presentation, 2nd International Conference on Transposition, Minneapolis, MN. June 1-2.
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