Research Interests
Utilizing molecular
biology and muscle cell culture methodologies to study the regulation
of muscle growth during embryonic and postnatal growth of economically-important
animals, currently focusing on the two research areas: 1) Mechanism
of Action of Anabolic Steroid Growth Promoters, 2) Role
of Insulin-like Growth Factor Binding Proteins in Growth and Differentiation
of Pig Muscle Cells.
Teaching
- ANSC 3511: Animal Growth and Development (guest lecturer)
- ANSC 4096: Professional Exp (Internship) (advisor)
- ANSC 8344: Mechanisms of Hormone Action (guest lecturer)
- ANSC 8510: Graduate Seminar
Current Graduate Student and Post-doctoral Supervision
- Melvin Pagan (co-supervise),
Post-doctorate
- Ernest I. Kamanga-Sollo (co-supervise), Post-doctorate
- Mary Pampush (co-supervise), Post-doctorate
- Xi Gang (co-supervise), Ph.D. candidate
Professional
Activities and Honorary Societies
- Member,
Committee to Rewrite the NC-131 Regional Project
- Member,
Tech. Comm. NC-131 Regional Project, Molecular Mechanisms Regulating
Skeletal Muscle Growth and Differentiation
- Reviewer,
USDA Competitive Grant Proposals
- Student
Advisor, President's Distinguished Faculty Mentor Program
- Member,
American Society of Animal Science
- Phi
Kappa Phi
- Gamma
Sigma Delta
Publications
(2007-2011)
- Refereed Articles -
Kamanga-Sollo, E., M.E. White, M.R. Hathaway, W.J. Weber, and W.R. Dayton. 2011. Effect of trenbolone acetate on protein synthesis and degradation rates in fused bovine satellite cell cultures. Domest. Anim. Endocrinol. 40(1):60-66. Epub 2010 Sep 29.
Pampusch, M.S., E. Kamanga-Sollo, M.R. Hathaway, M.E. White, and W.R. Dayton. 2011. Low-density lipoprotein-related protein 1 (LRP-01) is not required for insulin-like growth factor binding protein 3 (IGFBP-3) to suppress L6 myogenic cell proliferation. Domest. Anim. Endocrinol. Feb. 11, 2011 [Epub ahead of print]. PMID: 21353438.
Kamanga-Sollo, E., M.E. White, M.R. Hathaway, W.J. Weber, and W.R. Dayton. 2010. Effect of estradiol-17β on protein synthesis and degradation rates in fused bovine satellite cell cultures. Domest. Anim. Endrocrinol. 39:54-62.
Dayton, W.R. and M.E. White. 2008. Cellular and molecular regulation of muscle growth and development in meat animals. J. Anim. Sci. 86(14 Suppl):E217-E225. Epub 2007 Aug. 20.
Kamanga-Sollo, E., M.E. White, K.Y. Chung, B.J. Johnson, and W.R. Dayton. 2008. Potential role of G-protein-coupled receptor 30 (GPR30) in estradiol-17β-stimulated IGF-I mRNA expression in bovine satellite cell cultures. Domest. Anim. Endocrinol. 35(3):254-262. Epub 2008 Jul. 11.
Kamanga-Sollo, E., M.E. White, M.R. Hathaway, K.Y. Chung, B.J. Johnson, and W.R. Dayton. 2008. Roles of IGF-I and the estrogen, androgen and IGF-I receptors in estradiol-17β and trenbolone acetate- stimulated proliferation of cultured bovine satellite cells. Domestic Anim. Endocrinol. 35:88-97.
Pampusch, M.S., M.E. White, M.R. Hathaway, T.J. Baxa, K.Y. Chung, S.L. Parr, B.J. Johnson, W.J. Weber, and W.R. Dayton. 2008. Effects of implants of trenbolone acetate, estradiol, or both, on muscle IGF-I, IGF-I receptor, estrogen receptor-α and androgen receptor mRNA levels in feedlot steers. J. Anim. Sci. 86:3418-3423.
Xi, G., M.R. Hathaway, W.R. Dayton, and M.E. White. 2007. Growth factor messenger ribonucleic acid expression during differentiation of porcine embryonic myogenic cells. J. Anim. Sci. 85:143-150.
Xi, G., M.R. Hathaway, M.E. White, and W.R. Dayton. 2007. Localization of insulin-like growth factor (IGFBP)-3 in cultured porcine embryonic myogenic cells before and after TGF-beta(1) treatment. Domest. Anim. Endocrinol. 33(4):422-429.
- Abstracts -
Kamanga-Sollo, E., M.E. White, M.R. Hathaway, W.J. Weber, and W.R. Dayton. 2010. Effect of estradiol-17β on protein synthesis and degradation rates in fused bovine satellite cell cutures. J. Anim. Sci. 88 (E-Suppl. 2):634.
Kamanga-Sollo, E., M.E. White, M.R. Hathaway, W.J. Weber, and W.R. Dayton. 2010. Effect of trenbolone acetate on protein synthesis and degradation rates in fused bovine satellite cell cultures. J. Anim. Sci. 88 (E-Suppl. 2):634.
Kamanga-Sollo, E., M.S. Pampusch, M.E. White, M.R. Hathaway, and W.R. Dayton. 2009. Potential role of low-density lipoprotein receptor-related protein (LRP-1) and IGFBP-3 in the proliferation-suppressing actions of TGF-beta on cultured myogenic cells. J. Animal Sci. 87(E-Suppl. 2):236.
Kamanga-Sollo, E., M.E. White, M.R. Hathaway, K.Y. Chung, B.J. Johnson, and W.R. Dayton. 2008. Effects of androgen and estrogen (E2) receptor blockers and E2-conjugated BSA on estrogen and trenbolone acetate-stimulated IGF-I expression in cultured bovine satellite cells. J. Anim. Sci. 86 (E-Suppl. 1):428.
Kamanga-Sollo, E., M.E. White, M.R. Hathaway, K.Y. Chung, B.J. Johnson, and W.R. Dayton. 2008 Roles of increased IGF-I expression and the estrogen, androgen and IGF-I receptors in estradiol-17β and trenbolone acetate- stimulated proliferation of cultured bovine satellite cells. J. Anim. Sci. 86 (E-Suppl. 2):427.
Pampusch, M.S., M.E. White, M.R. Hathaway, K.Y. Chung, B.J. Johnson, and W.R. Dayton. 2008. Effects of trenbolone acetate (TBA), Estradiol (E2) and combined TBA/E2 implants on muscle IGF-I and IGF-II mRNA levels in feedlot steers. J. Anim. Sci. 86 (E-Suppl. 2):427.
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