Education
- Ph.D., University
of Illinois, Quantitative Genetics
- M.S., Iowa State University, Statistics
- MS, Beijing Agricultural University, Quantitative Genetics
Research
Interests
- Statistical genetics and genomics.
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Statistical analysis for mapping disease genes and quantitative trait loci.
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Statistical procedures to apply genetics markers to animal breeding and genetics.
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Genetic diversity in domestic animals.
Software Tools
http://animalgene.umn.edu
Graduate Training
Teaching
Publications (2005-2009)
- Refereed Articles -
Ma, L., H.B. Runesha, D. Dvorkin, J.R. Garbe, and Y. Da. 2008. Parallel and serial computing tools for testing single-locus and epistatic SNP effects of quantitative traits in genome-wide association studies. BMC Bioinformatics 9:315. Article URL: http://www.biomedcentral.com/1471-2105/9/315.
Gao, Y., X.X. Hu, Z.Q. Du, X.M. Deng, Y.H. Huang, J. Fei, J.D. Feng, Z.L. Liu, Y. Da, and N. Li. 2006. A genome scan for quantitative trait loci associated with body weight at different developmental stages in chickens. Animal Genetics 37:276.
Huang, Y.Q., X.M. Deng, Z.Q. Du, X. Qiu, X. Du, W. Chen, M. Morisson, S. Leroux, F.A. Ponce de León, Y. Da, and N. Li. 2006. Single nucleotide polymorphisms in the chicken Lmbr1 gene are associated with chicken polydactyly. Gene. 2006 Apr. 28.
Mao, Y., N.R. London, L. Ma, D. Dvorkin, and Y. Da. 2006. Detection of SNP epistasis effects of quantitative traits using an extended Kempthorne model. Physiological Genomics 28: 46-52.
Henderson, D., M. Thomas, and Y. Da. 2005. Conference review: Bovine genomics from academia to industry. Comparative and Functional Genomics 6:174-180.
Mao, Y. and Y. Da. 2005. Statistical power for detecting epistasis QTL effects under the F-2 Design. Genetics, Selection, Evolution 37:129-150.
- Invited Papers, Conference Proceedings, Research Reports -
Ma, L., D. Dvorkin, J.R. Garbe, and Y. Da. 2007. Genome-wide analysis of single-locus and epistasis SNP effects on anti-cyclic citrullinated peptide as a measure of rheumatoid arthritis. BMC Proceedings:1(Suppl. 1):S127.
London, N. and Y. Da. 2006. Statistical power and sample size requirement for QTL detection. In: Proc. of the 8th World Congress on Genetics Applied to Livestock Production, edited by B.D. Valente, O. Rossi de Morais, and R.V. Ventura. Belo Horizonte, Brazil: Instituto Prociência. Vol. 22: Article #18.
Ma, L., D. Dvorkin, and Y. Da. 2006. Genome-wide analysis of single-locus and epistasis SNP effects on anti-cyclic citrullinated peptide. In: Participant Contributions, Genetic Analysis Workshop 15, pp. 13-54 ~ 13-56. St. Petersburg Beach, FL. Nov. 12-15.
Mao, Y. and Y. Da. 2006. Statistical power and sample size for QTL detection using flanking markers under the f-2 design. In: Proc. of the 8th World Congress on Genetics Applied to Livestock Production, edited by B.D. Valente, O. Rossi de Morais, and R.V. Ventura. Belo Horizonte, Brazil: Instituto Prociência. Vol. 23: Article #19.
- Books, Textbooks and Monographs -
Y. Da. 2007. Statistical Genetics and Genomics. Department of Animal Science, University of Minnesota.
Ma, L., D. Dvorkin, and Y. Da. 2006. EpiSNP User Manual Version 1.0w. Department of Animal Science, University of Minnesota. http://animalgene.umn.edu.
Garbe, J.R. and Y. Da. 2005. Pedigraph user manual Version 2.2. Department of Animal Science, University of Minnesota. Http://animalgene.umn.edu.
- Abstracts -
Sonstegard, T.S., L. Ma, J.B. Cole, G.R. Wiggans, B.A. Crooker, C.P. Van Tassell, B. D. Mariani, and Y. Da. 2009. Genome signature of artificial selection for milk yield in Holstein cattle. (Poster Presentation.) Plant and Animal Genome XVII, San Diego, CA. Jan. 10-14.
Sonstegard, T.S., L. Ma, J.B. Cole, G.R. Wiggans, B.A. Crooker, C.P. Van Tassell, B.D. Mariani, P.M. Van Raden, M.V. da Silva, and Y. Da. 2008. Genomic signatures of artificial selection in U.S. Holstein cows. (Oral and Poster Presentation.) The Conf. of International Society of Animal Genetics, Amsterdam, The Netherlands. July 20-24.
Duan, Y., J. Garbe, N. London. L. Ma, and Y. Da. 2006. A computer program for detecting additive, dominance, imprinting, sex-influenced and the overall QTL effects. Abstract #32, Joint Ann. Mtg. of American Dairy Sci. Assoc. and American Animal Sci. Assoc., Minneapolis, MN.
Ma, L., D. Dvorkin, and Y. Da. 2006. Large scale SNP epistasis detection of complex traits using pairwise epistasis tests. IGES 15th Ann. Mtg. Nov. 16-17, St. Pete Beach, FL. p. 55.
Da, Y. and Y. Mao. 2005. Detection of epistasis effects of biallelic candidate genes of complex traits. Program and Abstract Book, p.55, Human Genome Meeting, April 18-21, 2005, Tokyo.
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