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Milena Saqui-Salces

Milena Saqui-SalcesAssistant Professor
Gut Cellular Physiology

Department of Animal Science
495K Animal Science/Veterinary Medicine Building
1988 Fitch Avenue
St. Paul, MN 55108-6014
Telephone: 612-624-4277
Fax: 612-625-2743
Email: msaquisa@umn.edu

Education

Post-doctorate: University of Michigan - Physiopathology of the GI Tract
PhD: Universidad Nacional Autonoma de Mexico (UNAM) - Biological Science
BS: Instituto Technologico de Veracruz - Biochemical Engineering

Research Interests

The endocrine function of the gastrointestinal tract is my main research interest. I reported for the first time that endocrine cells of the stomach that secrete gastrin, ghrelin and somatostatin have primary cilia. Primary cilia are sensory organelles that work as antennas that the cells use to sense their immediate environment and to regulate signaling pathways. Cilia in gastrin-secreting cells are associated to sensing luminal components of food that affect gastrin release. I have also found that the alteration of gastrin and gastric acid secretion leads to the development of obesity and fatty liver in mouse models. The goal of my research is to understand the cells and mechanisms involved in sensing components of food and hos those luminal signals (food) mediate GI hormone secretion and participate in metabolic homeostasis and the development of obesity.

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