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College of Food, Agricultural and Natural Resource Sciences
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Department of Animal Science

Home > People > Faculty > Laura J. Mauro

Laura J. Mauro

Dr. Laura J. MauroAssociate Professor

Department of Animal Science
495F An Sci/Vet Med
1988 Fitch Avenue
St. Paul, MN 55108-6014
Telephone: 612-624-6274
Fax: 612-625-2743
Email: mauro002@umn.edu

Education

Research Interests

The phosphorylation and dephosphorylation of cellular proteins is a critical component in the regulation of all biological processes. The signaling molecules known as protein tyrosine kinases and phosphatases are essential mediators of this type of regulation. They are responsible for maintaining a steady-state level of specific phosphotyrosine proteins which will influence the functional state of the cell. Mutations or dysfunction in these molecules is associated with many animal and human diseases including deadly bacterial infections, diabetes, and cancer. My laboratory studies the importance of the tyrosine phosphatases (PTPs) in cell proliferation and differentiation. We are interested in how certain PTPs regulate cell growth and differentiation during the development and remodeling of bone. In addition, we are exploring whether these molecules could serve as drug targets for skeletal disorders, such as osteoporosis, in animals and humans.

Teaching

Outreach

Honors and Awards

    

Links

Publications

UM Cancer Center

UM Center on Aging

Graduate Program in Biochemistry, Molecular Biology & Biophysics

Graduate Program in Molecular Veterinary Biosciences